Development and biopharmaceutical evaluation of extended release formulation of tramadol hydrochloride based on osmotic technology
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چکیده
منابع مشابه
Development and biopharmaceutical evaluation of extended release formulation of tramadol hydrochloride based on osmotic technology.
Extended release formulation of tramadol hydrochloride (TRH) based on osmotic technology was developed and evaluated. Target release profile was selected and different variables were optimized to achieve it. Formulation variables such as the level of swellable polymer, plasticizer and the coat thickness of semipermeable membrane (SPM) were found to markedly affect drug release. TRH release was ...
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15 صفحه اولFormulation Development and Evaluation of Mouth Dissolving Tablet of Tramadol Hydrochloride
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ژورنال
عنوان ژورنال: Acta Pharmaceutica
سال: 2009
ISSN: 1846-9558,1330-0075
DOI: 10.2478/v10007-009-0010-2